Thursday, April 12, 2012

Annan says Syria promises to respect ceasefire

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nicki minaj beez in the trap video

Verizon HTC Incredible 4G gets press render, sheepishly grins for Mr. Blurrycam

HTC Incredible 4G sheepishly grins for Mr. Blurrycam
Promise not to laugh, folks, because this one appears a bit camera shy: meet the HTC Incredible 4G for Verizon Wireless. As you can see, the designers have kept the same industrial, funky and yet austere style as before, and like the original, the famous red accents are back in the mix. The camera pod continues to exist as part of a larger protrusion on the back, which now sports a significant amount of texture. The number of capacitive buttons on the front has been reduced to three, with search now absent. The Incredible 4G is is most certainly an Ice Cream Sandwich device, complete with a Sense 4 overlay.

A quick peek at the hardware information reveals a dual-core 1.2GHz CPU, 1GB of RAM, 8GB of built-in storage, an 8MP primary camera and a front-facing VGA counterpart, along with 802.11a/b/g/n and Bluetooth 4.0 -- as well as support for LTE, NFC and WiFi Direct. The display is estimated at 4-inches and is said to offer qHD resolution. In highly welcome bit of news, the camera is said to capture a rapid burst of images, which gives us hope that this is the same option found on the One X and One S. Nonetheless, it appears to be a mainstream, middle-of-the-road handset that will likely be priced between $100 and $150 on-contract. Be sure to hop the break for the press render, and for a few extra blurry snapshots, just hit up the source link below.

Continue reading Verizon HTC Incredible 4G gets press render, sheepishly grins for Mr. Blurrycam

Verizon HTC Incredible 4G gets press render, sheepishly grins for Mr. Blurrycam originally appeared on Engadget on Wed, 11 Apr 2012 18:03:00 EDT. Please see our terms for use of feeds.

Permalink   |  sourceAndroid Police, Pocketnow  | Email this | Comments


dallas tornado video

Google Currents app updated with international support, offline reading

Google Currents app updated with international support, offline reading
Folks in the US have been able to use the Google Currents app to read various websites (including this one) with more of a magazine-style layout since late last year, and now those outside the country can finally get in on the act as well. Google has today rolled out version 1.1 of the app for Android and iOS, which makes the service available worldwide with support for 44 languages, and adds a number of other improvements including the ability to select which editions have images for offline reading, instant online sync, translation for 38 languages and a promised 7X performance boost. As before, the app is completely free, and adapts the layout to suit both phones and tablets. Hit the links below to download it for the platform of your choice.

Google Currents app updated with international support, offline reading originally appeared on Engadget on Wed, 11 Apr 2012 17:06:00 EDT. Please see our terms for use of feeds.

Permalink   |  sourceGoogle Mobile Blog, Google Play, iTunes  | Email this | Comments

patrice o neal

Preventive Measure for Mosquito | Health and Fitness Blog

Mosquitoes can be extremely threatening because the insects are equipped for multiplying in a rapid rate plus cause diseases like malaria and chikungunya. There are numerous pest management methods which might be taken up with the eradication of such insects inside an effective and affordable manner.

Mosquito breeding usually is whithin areas with standing or stagnant water and as such removing these kinds of sources is the better way to stop multiplication of the. Make sure that all drainage areas are closed and sealed and as well remove objects like old tires, used cans, buckets and barrels, that can collect water and turn a breeding ground of these insects.

When you have an artificial pond, fountain, bird bath or pool at home, make certain you clean these regularly to ensure that no larvae exists which can breed into mosquitoes. For those who have a natural pond, lake, well and other water body near the house, then introduce species of fish that feast upon mosquito larvae and thereby assistance in preventing the rapid breeding.

Yet another simple method to stop breeding is to apply oils to coat the counter of water that could increase the surface tension and stop the larvae and pupae from getting air for breathing. In case your area is afflicted with any of the mosquito borne diseases like dengue or malaria, you then must report this to your health authorities. Usually chemical pesticides are sprayed in these areas to crush existing larvae and pupae that could bring down the menace.

This method requires specialized equipment so because of this must simply be carried out by professional pest control experts. The spraying procedure is frequently carried out in the evenings when these insects are most active. Care also needs to be taken that high concentrations with this chemical spray aren\?t used which is toxic for individuals and pets.

In areas tormented by mosquitoes, personal protection can be very important to avoid diseases. Make certain you wear clothes that go over your body completely especially arms or legs. Keep the doors and windows shut from early evening to counteract these insects from entering your own home. Fans can be effective than air conditioning equipment can in preventing these insects from biting you because they cannot fly about in moving air. Also you can attach insecticides coated mosquito nets to line the windows, air pockets and doors to stop the entry these. In some places, such nets can also be found for use on beds and cradles which may be used during sleep.

No comments yet.

hoya

Mood Drug Can Both Cause and Relieve Anxiety

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If you have ever jumped at a loud noise and felt an adrenaline rush, you have experienced the effects of corticotropin-releasing hormone (CRH). In the body, this hormone triggers the familiar fight-or-flight response--racing heart, shortness of breath, sweaty palms. In the brain, however, it acts as a chemical messenger, playing a role in anxiety and depression. That role, a new study suggests, is more complex than anyone expected.

[More]

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hypertrophic cardiomyopathy

Zimmerman to be charged in Trayvon Martin?s death

A rally for Trayvon Martin; George Zimmerman in an recent, undated photo (AP)

Angela Corey, the special prosecutor investigating the shooting death of Trayvon Martin, is scheduled to hold a 6 p.m. EDT press conference in Jacksonville, Fla., on Wednesday, where she is expected to charge George Zimmerman in the 17-year-old's killing.

According to the Associated Press, Zimmerman will be charged with 2nd-degree murder. Corey's office confirmed the press conference but did not elaborate on the details. According to the AP, Zimmerman is in custody. According to CNN, he turned himself in.

The announcement comes a day after Zimmerman's attorneys said that they were dropping the case because their client had stopped communicating with them. On Sunday, Zimmerman launched a website seeking donations for his legal and living expenses.

Zimmerman, a neighborhood watchman, shot and killed Martin on Feb. 26 in Sanford, Fla., a gated community outside of Orlando. He told police he was attacked by Martin and was acting in self-defense.

Earlier this week, Corey announced the case would not go to a grand jury.

Other popular Yahoo News stories:

? George Zimmerman attorneys quit as counsel

? Trayvon Martin shooting: no grand jury for Zimmerman

? Trayvon Martin case exposes worst in media

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jaws

Cow escapes NJ slaughterhouse, will be spared

(AP) ? A cow that escaped from a New Jersey slaughterhouse will be spared.

The black-and-white bovine was running through the streets of Paterson sometime after 8 p.m. Tuesday.

Animal control officer John De Cando tells The Record newspaper (http://bit.ly/IqWC6F) it was like "Dodge City" with police cars trying to corral the 750-pound animal. But the cow managed to break loose.

De Cando tranquilized the cow after it became trapped between a fire hydrant and a truck.

De Cando says the slaughterhouse owner has promised to take the animal to a farm.

No one was injured.

___

Information from: The Record, http://www.northjersey.com

the duchess

Facebook Fan Webpages ? Essential to Social Media Internet ...

A phrase ?Social Media? is all over all these days, and in case you are similar to me, you might be a little unclear about what it really is? the well known phrase ?I?ll know it when I see it? comes right away to my brain!

Among the highly effective factors about using a Social Media Marketing site is the fact many of them provide a level playing field when it comes to small businesses versus the big boys. For example, you are able to buy facebook fans to your offline organization and thus can a significant automobile company. Within those Facebook Fan pages, you and the multiple billion dollar vehicle producer have the similar tools and also sources. Upon Tweets, as another case, you and the large companies are limited to a hundred and forty characters per tweet. They can?t purchase much more characters and also blast you out of the competition.

Once considering which Social media marketing web-site to make use of Social internet marketing, you should consider the web site?s membership however you must also evaluate its culture and the way the people communicate. It is essential that any Social Media Marketing web site get a human population whose interests are usually in range with your objectives and, additionally, that it use a shape and also routine of interaction that is works with your targets.

With WordPress as the website management program, once you have signed up for the particular Networked Blogs Fb Appllication, it is possible to arranged your site to show any kind of modifications on your Fb Fan Page by Get Facebook Fans along with your Twitter accounts. Your Twitter Profile could be arranged to exhibit Facebook Fan Page Comments along with Posts from your WordPress website. Additionally, your Twitter posts will probably be displayed on your Fb Fan Page along with your website.

To learn more about Facebook fans and read extra posts and knowledge check out online website socialmediacorp.org to find much more about twitter followers and also youtube audiences.

Related posts:

  1. Prosperous Providers Are Working with Social Media Marketing To acquire Their Message Across Are you?
  2. Tips To Make Social Media Marketing Easier
  3. Use These Tips For Simpler Social Media Marketing
  4. Use Social Media Advertising And Marketing To Have New Business
  5. Enhancing Your Bottom Line With Social Media Marketing

west virginia

Avoid Home Foreclosure With a Debt Management Plan | Financial ...

Avoid Home Foreclosure With a Debt Management Plan

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A Debt Management Program will let you get back together Through Track

A non-profit Plastic counseling Commerce can help you in many different ways. 1 A few of the All Massive resources Would be To get a debt management program. Practiced counselors utilising Those To generate a Completely new Investment banking management Plan of action Where it works. Would Last Easy and convenient dating profile money that you just do have an overabundance of effectively. nonprofit Credit worthiness counselors may expertise Your main Banking institutions Structure Some Regular money A good deal affordable. this is done Just Fighting for rates of return in addition to search terms house services Extraordinary creditors. Each and every You may have Certainly gotten Causing on top of your bills, Develop their creativity Generally Regimen a good solid Coverage that will actually stop you above Additional Will not likely trouble.
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fracking

SmartTouch Interactive Provides Real Estate Marketing Services ...

SmartTouch Interactive Provides Real Estate Marketing Services and Tools to ?
Wycliffe Homes in Canada has engaged the company to develop interactive lead generation programs and provide the SmartTouch Platform as a tool to help its sales and marketing teams gather deeper intelligence and improve conversion rates.
Read more on EON: Enhanced Online News (press release)

Industry Veteran Patrick Gault Joins Ekinops as Vice President of Sales for ?
PARIS, Apr 10, 2012 (BUSINESS WIRE) ? Ekinops, a leading supplier of next-generation optical transport equipment, announced today the appointment of Patrick Gault, previously with Tellabs and Cisco, to the position of vice president of sales for the ?
Read more on MarketWatch (press release)

Tablet Sales to Skyrocket in 2012, Apple To Keep Lead
Sales of tablets built using Google's Android OS (including the Kindle) totaled 17.3 million units. The gap is projected to keep growing, even with Microsoft entering the fray. Apple's tablet sales, led by demand for the new third-generation iPad ?
Read more on Forbes

golden globe nominations

Wednesday, April 11, 2012

Dementia cases 'to double by 2030': WHO

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randy moss

HSBC Reaffirmation Agreements Don't Quite Add Up: Are the Errors ...

reaffirmation scam

I've got a reaffirmation agreement to sell you...

Problems With Reaffirmation Agreements of HSBC Subsidiary

A couple months ago, I got a call from a prospective client (who we?ll call Jim). At the time he called, Jim was involved in a pro se adversary case involving a dispute over the terms of a reaffirmation agreement. As I learned more and dug deeper, it started to look more and more likely that there was something going on in Jim?s case that didn?t pass the smell test. I?ve outlined the important facts of the case below so bankruptcy attorneys will be on the lookout for these types of reaffirmation schemes in their jurisdictions.

Pro Se Debtor Contacted About Mortgage ?Modification?

In 2010, Jim filed a pro se chapter 7 bankruptcy case stating his intention to surrender his underwater home. At the time of the bankruptcy, Jim?s home was in foreclosure, but had not yet been sold. Before Jim received his bankruptcy discharge, he was contacted by a representative at Household Finance Corporation II, a subsidiary of HSBC, who called to gauge his interest in reaffirming his mortgage debt. After many failed attempts at a modification, Jim was surprised that Household Finance offered to slash his interest rate from 10.99% to 5.25% while he was in bankruptcy, but he found the modified rate too attractive to pass up and agreed to reaffirm the debt.

Letters From Lawyers

In October, 2010, Jim received a letter and form reaffirmation agreement from John D. Schlotter of Aldridge & Connors, LLP in Atlanta, GA. Aldridge & Connors represents Household Finance Corp. in reaffirmation proceedings nationwide. Mr. Schlotter explained in his cover letter that the reaffirmation agreement contains

a ?rate modification reducing the annual interest rate on this loan to a fixed rate of 5.25%.? Mr. Schlotter goes on to explain that ?if the amount of income is less than total expenses, leaving a balance less than the amount needed for the monthly mortgage payment, then a presumption of undue hardship arises and an explanation must be provided.?

The Reaffirmation Hearing

Jim (remember he was pro se) amended his bankruptcy schedules, including Schedule J, to reflect the reaffirmation payments and motioned the Court to approve the reaffirmation agreement. A hearing was required because Jim was not represented by an attorney and the addition of the monthly mortgage payment put his monthly expenses approximately $2,500 below his monthly income. In November, 2010, the Bankruptcy Judge approved Jim?s reaffirmation agreement, but not without some hesitation. In rebutting the presumption of undue hardship, Jim pointed out that he was to receive a car from family and would therefore be able to surrender his current automobile to cut expenses. According to Jim, the Judge commented that ?this was one of the largest reaffirmation agreement payments he had approved?, but approved nonetheless on the strength of Jim?s amended budget which, after surrendering the car, still showed a monthly shortfall in expenses versus income.

The Trouble Begins?

Approximately five days before receiving his discharge order, the trouble began. Jim received a letter informing him of his right to cure defaults under the reaffirmation agreement as well as his first invoice for approximately $13,000 which included back property taxes paid by Household Finance Corporation, II. This was the first invoice Jim ever received. He was surprised to learn that he was already in default and that he was being charged for back taxes not disclosed in the reaffirmation agreement. The invoice was more than $10,000 above what he?d agreed to. Notably, section B of the reaffirmation agreement specified the amount reaffirmed as $617,892.92, which was Jim?s mortgage balance, including interest and penalties. By the reaffirmation agreements? express terms, the amount reaffirmed incorporated ?the entire amount? including ?unpaid principle, interest, and fees and costs (if any)? which arose on or before the date of the reaffirmation disclosure statement. Back taxes were not disclosed as a cost or fee.

Payments Don?t Add Up to the Amount Reaffirmed

With his suspicions raised, Jim found additional problems with his reaffirmation agreement. He realized that the sum of his payments amounted to a total far greater than what he?d agreed to reaffirm. Jim agreed to an annual interest rate of 5.25% on reaffirmed mortgage debt of $617,892. He agreed to make payments of $2,268.64 per month for 328 months starting in the month after the filing of the reaffirmation agreement. However, under the payment schedule listed in the reaffirmation agreement (328 payments of $2,268.64) he would pay $744,212.32 not $617,892 as he agreed. Over the life of the reaffirmation agreement, he was being overcharged by $126,320.32!

There Seems to be a Pattern

As Jim investigated further on PACER, he found repeated irregularities with Household Finance Corporation reaffirmation agreements in numerous states. Some, like his, overcharged. Others contained amortization schedules that fell far short of the amount reaffirmed, leaving borrowers with an undisclosed balloon payment at the end of their repayment term. A lump sum payment that would almost certainly push many of them into foreclosure, just at the time they though they had their home paid off. ?Outraged, Jim filed an adversary case, again pro se. It wasn?t until just before the Judge decided to throw out the reaffirmation agreement as void due to mistake that I caught wind of what was going on. I imagine that other Bankruptcy Courts would take a very different approach if they knew that the problems with Household Finance Corporation reaffirmation agreements are systemic and not just an isolated scriveners error. In all the cases Jim and I took a look at, we didn?t once see a Household Finance mortgage reaffirmation that added up to the actual amount reaffirmed.

HSBC?s ?Position?

In Jim?s adversary case,?HSBC argued that deferred interest payments of approximately $150,000 as well as attorneys? fees of approximately $10,000 were due and payable at the ?end of the repayment term? per the reaffirmation agreement contract. They also contended that additional fees were owed on top of Jim?s monthly payment (presumably why his first invoice was high by more than $10,000). HSBC makes an interesting argument because none of the fees they claim Jim owes were disclosed anywhere in his reaffirmation contract. Per section 524(K)(3)(C)(ii) of the Bankruptcy Code the ?Amount reaffirmed? must include the total of ?any fees and costs accrued as of the date of the disclosure statement.??Was HSBC arguing that Jim owed more in fees, even after the bloated monthly payments ceased? I?m not sure even they know, but here is a quote from their pleadings:

?Plaintiff was unaware of these existing repayment obligations under the reaffirmation agreement and filed this lawsuit because he never intended to be liable for the additional amounts that defendants seek to collect?in addition to the 328 payments of $2268.64 for principal and interest under the reaffirmation agreement.?

In addition to the 328 payments of $2,268.64? Really? The reaffirmation cover sheet?listed $0.00 in ?monthly payments not listed on Schedule J.??Certainly something debtor?s attorneys may want to look into.


Questions about debt?Ask An Attorney

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3370 WESTMOUNT RD, West Vancouver - House/Single Family ...

View more homes for sale in West Vancouver - Click here

3370 WESTMOUNT Road | West Vancouver, BC | V7V 3G6 | Westmount WV

  • Street Address: - 3370 WESTMOUNT Road
  • Area/City: West Vancouver
  • Community: Westmount WV
  • Postal Code: V7V 3G6
  • MLS? V942229
  • Property Type: House/Single Family
  • Property Style: "2 Storey"
  • Taxes: $3900.0/2011
  • Approx Year Built: 1960
  • Bedrooms: 4
  • Bathrooms: 3
  • Total Floor Area (sqft): 3012
  • Lot Size (sqft): 13222.000
  • Frontage (feet): 79.000
  • Depth (feet): 181/149
  • Title to Land: Freehold NonStrata
  • Name of Complex:
  • Listing provided by: RE/MAX Masters Realty
  • Board: Real Estate Board of Greater Vancouver

Sensational private park-like yard engulfs this spacious family home in West Bay. With the open floor plan, your kitchen looks out over your huge deck (boasting an 8 person hot tub!) onto your manicured lawn and peek-a-boo view. With 4 beds and 3 baths this home was designed with family and entertaining all in one! Bright and cheery is what comes to mind the moment you walk through the front door.

"Private Setting","Private Yard","Ski Hill Nearby","Recreation Nearby"


Don't hesitate to call for any additional information:
Joe Manhas 604-720-0438 or Rimpy Hothi 604-725-0017

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3370 WESTMOUNT Road, West Vancouver, British Columbia, Canada


Find House/Single Family homes for sale in West Vancouver over 52 years old
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Disclaimer: The data relating to real estate on this web site comes in part from the MLS Reciprocity program of the Real Estate Board of Greater Vancouver. Real estate listings held by participating real estate firms are marked with the MLSR logo and detailed information about the listing includes the name of the listing agent. This representation is based in whole or part on data generated by the Real Estate Board of Greater Vancouver which assumes no responsibility for its accuracy. The materials contained on this page may not be reproduced without the express written consent of the Real Estate Board of Greater Vancouver

Still have questions? Do not hesitate to call for any additional information:
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Sparrows Sing Higher To Pierce Urban Din

60-Second Science60-Second Science | More Science

White-crowned sparrows in San Francisco are singing in a higher pitch than they did in 1969 to be heard over louder traffic. Christopher Intagliata reports.

More 60-Second Science

City dwellers compete with the din of traffic to be heard. And it?s not just urban humans. Sparrows living in San Francisco's Presidio district actually tweet their tunes in a higher register than they did in the past, to be heard over the rumble of cars on the nearby Golden Gate Bridge. So says a study in the journal Animal Behavior. [David A. Luther and Elizabeth P. Derryberry, Birdsongs keep pace with city life: changes in song over time in an urban songbird affects communication]

Researchers compared white-crowned sparrow songs recorded in 1969 and 2005. Over that time span, ambient noise levels went up. And the bird calls were essentially the same?but the more recent one was higher in pitch. The change presumably allows the song to better penetrate the traffic noise.

The modern calls carry more weight with the birds too. Because when male sparrows heard the 2005 recordings played back in their territory, they responded more aggressively?swooping in on the speaker with a ?get outta here" chirp and flapping their wings at the suspected intruder.

The researchers say most species simply can't handle the noise and cramped habitats of the city, and head to the country. The adaptable sparrow, however, simply changed its tune.

?Christopher Intagliata

[The above text is a transcript of this podcast]


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Web-based tool produces fast, accurate autism diagnosis

Web-based tool produces fast, accurate autism diagnosis [ Back to EurekAlert! ] Public release date: 10-Apr-2012
[ | E-mail | Share Share ]

Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School

Researchers at Harvard Medical School have significantly reduced from hours to minutes the time it takes to accurately detect autism in young children.

The process of diagnosing autism is complex, subjective, and often limited to only a segment of the population in need. With the recent rise in incidence to 1 in 88 children, the need for accurate and widely deployable methods for screening and diagnosis is substantial. Dennis Wall, associate professor of pathology and director of computational biology initiative at the Center for Biomedical Informatics at Harvard Medical School, has been working to address this problem and has discovered a highly accurate strategy that could significantly reduce the complexity and time of the diagnostic process.

Wall has been developing algorithms and associated deployment mechanisms to detect autism rapidly and with high accuracy. The algorithms are designed to work within a mobile architecture, combining a small set of questions and a short home video of the subject, to enable rapid online assessments. This procedure could reduce the time for autism diagnosis by nearly 95 percent, from hours to minutes, and could be easily integrated into routine child screening practices to enable a dramatic increase in reach to the population at risk.

"We believe this approach will make it possible for more children to be accurately diagnosed during the early critical period when behavioral therapies are most effective," said Wall.

This research will be published April 10 online in Nature Translational Psychiatry.

Autism is diagnosed through a careful analysis of an individual's behavior. When children are evaluated for autism, they typically take the Autism Diagnostic Interview, Revised, known as the ADI-R, a 93-question questionnaire, and/or the Autism Diagnostic Observation Schedule, known as the ADOS exam, which measures several behaviors in children. Together these evaluations can take up to three hours to complete and must be administered by a trained clinician. Often, there is a delay of more than a year between initial warning signs and diagnosis because of the waiting times to see a clinical professional who can administer the tests and deliver the formal diagnosis, Wall said.

Using machine learning techniques, an artificial intelligence method where machines are trained to make decisions, Wall and his team studied results of the ADI-R from the Autism Genetic Research Exchange for more than 800 individuals diagnosed with autism to find redundancies across the exam. They found that only seven questions were sufficient to diagnose autism with nearly 100 percent accuracy, equivalent to the full 93-question exam. They validated the accuracy of the seven question survey against answer sets from more than 1,600 individuals from the Simons Foundation and more than 300 individuals from the Boston Autism Consortium.

Wall applied similar techniques to the ADOS exam, this time classifying more than 1,050 individuals with near perfect sensitivity and slightly less than 95 percent specificity. The outcome of this work was not only a shortened mechanism for evaluating a child (8 out of 29 steps), but also a roadmap for evaluating short home video clips. Together these results have tremendous potential to move a substantial percentage of the effort into a mobilized electronic health framework with broad reach and applications.

"This approach is the first attempt to retrospectively analyze large data repositories to derive a highly accurate, but significantly abbreviated classification tool," said Wall, who is also associate professor of pathology at Beth Israel Deaconess Medical Center. "This kind of rapid assessment should provide valuable contributions to the diagnostic process moving forward and help lead to faster screening and earlier treatment," he said.

The traditional diagnostic surveys for autism can be prohibitive for families and caregivers because they are lengthy and have to be administered by a licensed clinician, often in an environment that is unfamiliar to the child, which can be a tremendous burden for families in remote areas, said Wall. "With this mobilized approach, the parent or caregiver will be able to take the crucial first steps to diagnosis and treatment from the comfort of their own home, and in just a few minutes."

Currently, Wall has made a survey and video site available to the public for free to continue evaluating the effectiveness of the shortened approaches and is working on ways to mobilize the overall approach to enable wide reach across the entire population in need. His team has also launched a Facebook page to spread the word and to share the survey more broadly. To date, 2,500 people have taken the Autworks survey.

###

--Katie DuBoff

Citation:

"Use of machine learning to shorten observation-based screening and diagnosis of autism" by Wall et al

Nature Translational Psychiatry, online publication, April 10, 2012

Harvard Medical School has more than 7,500 full-time faculty working in 11 academic departments located at the School's Boston campus or in one of 47 hospital-based clinical departments at 17 Harvard-affiliated teaching hospitals and research institutes. Those affiliates include Beth Israel Deaconess Medical Center, Brigham and Women's Hospital, Cambridge Health Alliance, Children's Hospital Boston, Dana-Farber Cancer Institute, Forsyth Institute, Harvard Pilgrim Health Care, Hebrew SeniorLife, Joslin Diabetes Center, Judge Baker Children's Center, Massachusetts Eye and Ear Infirmary, Massachusetts General Hospital, McLean Hospital, Mount Auburn Hospital, Schepens Eye Research Institute, Spaulding Rehabilitation Hospital, and VA Boston Healthcare System.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Web-based tool produces fast, accurate autism diagnosis [ Back to EurekAlert! ] Public release date: 10-Apr-2012
[ | E-mail | Share Share ]

Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School

Researchers at Harvard Medical School have significantly reduced from hours to minutes the time it takes to accurately detect autism in young children.

The process of diagnosing autism is complex, subjective, and often limited to only a segment of the population in need. With the recent rise in incidence to 1 in 88 children, the need for accurate and widely deployable methods for screening and diagnosis is substantial. Dennis Wall, associate professor of pathology and director of computational biology initiative at the Center for Biomedical Informatics at Harvard Medical School, has been working to address this problem and has discovered a highly accurate strategy that could significantly reduce the complexity and time of the diagnostic process.

Wall has been developing algorithms and associated deployment mechanisms to detect autism rapidly and with high accuracy. The algorithms are designed to work within a mobile architecture, combining a small set of questions and a short home video of the subject, to enable rapid online assessments. This procedure could reduce the time for autism diagnosis by nearly 95 percent, from hours to minutes, and could be easily integrated into routine child screening practices to enable a dramatic increase in reach to the population at risk.

"We believe this approach will make it possible for more children to be accurately diagnosed during the early critical period when behavioral therapies are most effective," said Wall.

This research will be published April 10 online in Nature Translational Psychiatry.

Autism is diagnosed through a careful analysis of an individual's behavior. When children are evaluated for autism, they typically take the Autism Diagnostic Interview, Revised, known as the ADI-R, a 93-question questionnaire, and/or the Autism Diagnostic Observation Schedule, known as the ADOS exam, which measures several behaviors in children. Together these evaluations can take up to three hours to complete and must be administered by a trained clinician. Often, there is a delay of more than a year between initial warning signs and diagnosis because of the waiting times to see a clinical professional who can administer the tests and deliver the formal diagnosis, Wall said.

Using machine learning techniques, an artificial intelligence method where machines are trained to make decisions, Wall and his team studied results of the ADI-R from the Autism Genetic Research Exchange for more than 800 individuals diagnosed with autism to find redundancies across the exam. They found that only seven questions were sufficient to diagnose autism with nearly 100 percent accuracy, equivalent to the full 93-question exam. They validated the accuracy of the seven question survey against answer sets from more than 1,600 individuals from the Simons Foundation and more than 300 individuals from the Boston Autism Consortium.

Wall applied similar techniques to the ADOS exam, this time classifying more than 1,050 individuals with near perfect sensitivity and slightly less than 95 percent specificity. The outcome of this work was not only a shortened mechanism for evaluating a child (8 out of 29 steps), but also a roadmap for evaluating short home video clips. Together these results have tremendous potential to move a substantial percentage of the effort into a mobilized electronic health framework with broad reach and applications.

"This approach is the first attempt to retrospectively analyze large data repositories to derive a highly accurate, but significantly abbreviated classification tool," said Wall, who is also associate professor of pathology at Beth Israel Deaconess Medical Center. "This kind of rapid assessment should provide valuable contributions to the diagnostic process moving forward and help lead to faster screening and earlier treatment," he said.

The traditional diagnostic surveys for autism can be prohibitive for families and caregivers because they are lengthy and have to be administered by a licensed clinician, often in an environment that is unfamiliar to the child, which can be a tremendous burden for families in remote areas, said Wall. "With this mobilized approach, the parent or caregiver will be able to take the crucial first steps to diagnosis and treatment from the comfort of their own home, and in just a few minutes."

Currently, Wall has made a survey and video site available to the public for free to continue evaluating the effectiveness of the shortened approaches and is working on ways to mobilize the overall approach to enable wide reach across the entire population in need. His team has also launched a Facebook page to spread the word and to share the survey more broadly. To date, 2,500 people have taken the Autworks survey.

###

--Katie DuBoff

Citation:

"Use of machine learning to shorten observation-based screening and diagnosis of autism" by Wall et al

Nature Translational Psychiatry, online publication, April 10, 2012

Harvard Medical School has more than 7,500 full-time faculty working in 11 academic departments located at the School's Boston campus or in one of 47 hospital-based clinical departments at 17 Harvard-affiliated teaching hospitals and research institutes. Those affiliates include Beth Israel Deaconess Medical Center, Brigham and Women's Hospital, Cambridge Health Alliance, Children's Hospital Boston, Dana-Farber Cancer Institute, Forsyth Institute, Harvard Pilgrim Health Care, Hebrew SeniorLife, Joslin Diabetes Center, Judge Baker Children's Center, Massachusetts Eye and Ear Infirmary, Massachusetts General Hospital, McLean Hospital, Mount Auburn Hospital, Schepens Eye Research Institute, Spaulding Rehabilitation Hospital, and VA Boston Healthcare System.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


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Video: The positive factors from the Santorum campaign



>> in brian will, david gregory and chuck todd . you heard rick santorum say this was an improbable race. in the end, he won 11 states. he said miracle after miracle. obviously balancing the issue of his beautiful little girl and her health crisis i as well as the reality, the numbers, and the money needed to keep going. the only number more than 11 is 1144 . that's that elusive delegate toll that they are all for. so notably, tamron, the name you did not hear in those remarks, as emotional as they were at times, was mitt romney . and these things are tough. it is tough after beating each other up for so many months in this extended gop campaign that no one foresaw. tough to come together at the end. and that kind of thing takes time. the romney campaign badly wants unity behind him. but as i mentioned it, chuck todd , a few minutes ago, coming out of, this you have karen santorum with a new fan base of her own. this lawyer who has raised seven kids who really was an appealing and powerful media presence for the campaign in the latter half. and of course, as the senator mentioned, you have bella who has her own fan base and led to so many people, especially parents of special needs people showing up at his rallies. a voice, a constituency that hasn't had someone to look to since sarah palin on the bottom of the mccain ticket.

>> that's a fantastic point. santorum said that they didn't trash anybody. i couldn't help but to think about this ad, for example, that's up in pennsylvania . mitt romney 's folks suspended the ad but basically it said that pennsylvania didn't want rick santorum as the senator and they don't want him to be the president. he specifically noted that he didn't trash anyone. and we know that we heard it from newt gingrich as well. a lot of that language they direct at mitt romney .

>> i can't hem but think that that ad in particular may be the reason that rick santorum kept mitt romney 's name out of his concession speech. it is one of those, it felt like piling on. you remember the romney campaign. they announced that they pulled it monday morning. but it had gotten some airing and it certainly was getting some, not a lot, but it was getting some airing. and as brian pointed out, these things are harder to get over for the candidates themselves. what is amazing here. usually, candidates get out a primary too late. when they should, in this case, i would say for santorum 's own political future, he got out at about as good of a time for his own political rehabilitation and his own political future going forward as he could have done. he went through it. made his last stand in wisconsin. it didn't work. he gets out before the possibility of embarrassing himself and losing pennsylvania .

>> let me bring you back in. we know within the hour the president will speak from florida on the buffett rule. this conversation of fairness or class warfare , depending on as you say, your perspective here. but newt gingrich is saying he is staying in the race. as reality forms into a one-on-one battle between mitt romney and president obama with the campaign even having that phone conference yesterday, wanting romney 's tax returns. wapgt romney to be clear on why they believe he wants middle class americans to pay more money. so this santorum suspension comes with all of this going on as well.

>> the general election campaign has already started. whether newt gingrich is still in the race or not he will conceded over the weekend that romney is likely the nominee so gingrich has to make up his own mind. he is keeping his voice alive and his ideas alive. one point about what they both mentioned about rick santorum not mentioning mitt romney , part of this is that he wants to be able to choreograph a little of how that endorsement unravels. the message we wants to push on romney . he won't give up that recognition and encoursement without some validation for some of the things he was about. that he wants governor romney to talk about. this is where the choreography come in. that will take some time. particularly because it's been so hard fought. if you are rick santorum , you still recognize that mitt romney , even as he could not sol dates the party around him. the governor of iowa today endorsing him. still has work to do to consolidate the base of the party. and santorum represents a lot of that.

>> and what he also represents, as he stated in his remarks, voice to the voiceless. one of the things repeatedly noted about rick santorum is this connection. the pennsylvania roots that he is able to articulate without a teleprompter. and just adlib his past and wind it into what a lot of people are going through, particularly in that rust belt . we saw it again today. the way he is able to connect. whether you agree with his ideology or where he stands, that connection factor that mitt romney critics say he just does not possess at this point.

>> that's right. first my last comments, i'm aware i just made sarah palin sarah palin a u.s. senator . this irony, this plays off what chuck was saying. that pennsylvania argument worked in so many places but was not likely to work in pennsylvania coming off that 18-point loss that so badly damaged rick santorum in the first place. he did what he did, 11 states worth, despite what happened to him in his home state. his departure from elective office. those arguments against the wealth of the romney campaign and his wealthy image, being able to talk about his roots and coal might know and being a veteran. the son of a veteran having served. that was all doing very well for him in the power corridor of the campaign there briefly.

>> chuck todd , we know that congressman ryan said a few week ago that this race has gone on long enough and he was worried it would start to damage mitt romney here. again, timing is everything. we know the conversation the president plans to have before the cameras in florida within the hour. how much damage, for example, the comments about health care with rick santorum saying that what was sign by mitt romney as governor of massachusetts and what is before the supreme court as they call owncare is the same thing. how much damage did he cause to mitt romney that perhaps will linger with independents, especially.

>> i think the damage he did was just financially extending this campaign. forcing romney to spend down final resources. he is way behind in getting the general election campaign going. getting on par with the campaign. that that, it would have been more damaging to mitt romney had he stayed in this race. had he gone through may. had he possibly won primaries in may and sort of lengthened the. a time that the romney campaign could fully put together. let's remember that some of the santorum 's rise had to do with mitt romney 's campaign skills. and a lot of it had to do with the fact that he was the last remaining viable anti- romney alternative in the conservative movement . and i think that that is what we'll try to figure out over the next four or eight years of how much of santorum 's support was pro santorum and how many of it was anti- romney .

jon hamm kim kardashian

Leumi demands repayment of NIS 189m Delek Real Estate debt

Delek Real Estate Ltd. (TASE: DLKR), controlled by Yitzhak Tshuva, yesterday announced that subsidiary Carmel Beach Resort 89 Ltd., which guarantees a debt of the company to Bank Leumi (TASE: LUMI), last Thursday received a demand from the bank to repay a debt of NIS 189 million. The bank added that non-payment would result in the liquidation of NIS 400,000 in deposits in Carmel Beach Resort's accounts at the bank.

Delek Real Estate added that Bank Leumi told it orally that besides offsetting these deposits, the bank was not demanding repayment of the balance of the debt to it.

Last week, the trustee of Delek Real Estate's Series 25 Bond, Adv. Guy Gissin, asked the court to appoint an attorney as an observer with no management rights in the company as liquidator in the event that the debt settlement proposed by the company did not result in a binding settlement.

The observer will be able to participate in all Delek Real Estate board meetings, to demand and receive documents and other items he needs, including items on company transactions in previous years, to appoint experts, and, in general, to ensure that company affairs are managed properly in a way that does not discriminate against any of its creditors.

Delek Real Estate's share price fell 1.6% by midday today to NIS 0.18, giving a market cap of NIS 72 million.

Published by Globes [online], Israel business news - www.globes-online.com - on April 9, 2012

? Copyright of Globes Publisher Itonut (1983) Ltd. 2012

jambalaya

A1 Answers Articles ? Marketing: The Success To Online Business ...

The modern world is evolving rapidly and a great way to assist with your money making endeavors is to look for great online business opportunities and then work hard at making them successful. Whenever you finish researching possible Internet businesses, you ought to have sufficient information to select the one which can provide exactly what you need regardless of whether it?s to replace a job, enable you to generate a reliable income working a couple of more hours or simply make a little more to have some additional money. Internet business possibilities can be found anywhere you look. Probably the most preferred business opportunities online develop from selling services but you must learn ways to market them to achieve success.

Online marketing abilities are something which each Internet business owner must acquire. Online marketing is among the most flourishing businesses on the Internet. Online marketing for business is one thing that will help to develop a wide range of earnings. Nowadays with technological developments the Internet is becoming a vital resource for millions of people all over the world. It really is believed that 10, if not more, millionaires are created through Internet success monthly, therefore making the world wide web accountable for the most created millionaires of any employer ever before.

Affiliate marketing and advertising is the promotion of varied services and products of other manufacturers and earning commissions though the generation of referred sales. Internet affiliate marketing is probably the simplest form of Internet business to get involved with. Internet affiliate marketing is definitely an online marketing strategy in which a company compensates its Internet marketer in accordance with the volume of revenue the affiliate generates. People can produce a business from Internet affiliate marketing by developing a website and becoming an affiliate marketer. When it comes to article promotion for the online home business, you have to evaluate the significant keywords and phrases which have various levels of competition on the Internet. With article promotion, it is very important to learn to be a proficient writer for the specialized niche or else you will end up hiring writers to do the work for you, which will decrease your profitability.

Websites, such as Elance, allow businesses to advertise their jobs. Web design service continues to be rated in the top five listings of growing Internet business possibilities by Entrepreneur magazine. Website hosting and website registry is really a unique industry altogether. Several individuals don?t understand the entire potential of Internet businesses simply because they overlook this very essential point in relation to creating an Internet business on the web. Another technique is to get your Internet website or blog listing near the top of the major search engines webpages when somebody researches a phrase or keyword that relates to your website. The greater website traffic you attract to your Internet business, the greater revenue it can produce and therefore the greater your income.

Related Posts

anne hathaway

Amazon makes the recipe for humanity available in the cloud

A partnership with the NIH gives genetics researchers access to thousands of human genomes

It's becoming more and more popular these days to back up your data to the?cloud. Your?iPhone does it. Your?tablet does it. And one day, perhaps soon, your doctor could be able to send a backup of?you to the cloud.

The concept sounds far fetched, but that's exactly what Amazon and the?National Institutes of Health (NIH) are up to. The collaborative effort is called the?1000 Genomes Project, and has already compiled 1,700 human?genomes ? essentially, the recipe for making 1,700 different people. Previously, this kind of data was only available to researchers by mailing data disks back and forth. The Amazon initiative now makes all that data available to genetic researchers via the?Amazon cloud.

Already, the project has amassed 200 terabytes worth of data on?human DNA, and is on track to add another 100 terabytes' worth of data soon. Researchers believe that by having so much data on human genetics readily available, they'll be better able to home in on the role genes play on disease. According to Matt Wood, head of the project at Amazon, "This is the seed to create a tree of data."

[via?Wired]

(Source)

This article was written by Fox Van Allen and originally appeared on Tecca

More from Tecca:

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Blog: Todd Scarbough - Fredric Gaines 47s blog - Nimer Jose62's blog

Todd Scarbough ?
It's Official: America is now
"More Obese than Ever"

More people are now "obese" rather than "just-plain-overweight"
100% of Americans predicted to be overweight by 2048

An interview with Mr. Arkansas and fitness trainer, Todd Scarborough

It's official. "Obese" Americans now outweigh the merely "overweight".
And together they crush the number of Americans with normal weights by over
a 2 to 1 margin.

A report issued by the National Center for Health Statistics shows that more than
34 percent of Americans have become "obese", compared to 32.7 percent who are
merely "overweight". The report said just under 6 percent are "extremely" obese.

"The figures show that America's obesity rate had more than doubled since 1980,"
says health and fitness educator Todd Scarborough.

Scarborough says perhaps even more dismaying are the numbers contained in a
study published in the journal Obesity.

"The study predicted that by 2030, 86% of all adults would be either overweight or
obese. By the year 2047, the study says 100% of Americans will be overweight or
obese if current trends continue," says Scarborough.

The CDC recently reported that 32 percent of U.S. children fit the definition of
being overweight, 16 percent were obese and 11 percent were extremely obese.

"Being overweight or obese not only reduces one's enjoyment of life, but it raises
the
risk of heart disease, diabetes, some cancers, arthritis, and premature death,"
says Scarborough. "We should all be taking these rising obesity statistics very
seriously."

Audio Interview Download:
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